5-Amino-1MQ

Research

5-Amino-1-Methylquinolinium

Aliases
5-Amino-1-methylquinolinium
Administration
Oral (research)

How it works

  1. Inhibits nicotinamide N-methyltransferase (NNMT) in fat and muscle cells

    It blocks an enzyme called NNMT that's been linked to how fat cells store energy.

  2. Increases intracellular NAD+ and SAM availability

    By blocking that enzyme, more of two important cellular molecules — NAD+ and SAM — stay available for the cell to use.

  3. Reduces adipocyte (fat cell) size in animal models

    In lab animals, this shrank the size of fat cells.

Result

Potential reduction in fat cell size and improved metabolic activity, based on animal research; human outcomes remain unknown. Since it hasn't been tested in people, there's currently no reliable basis for predicting how, or whether, someone would actually feel a difference.