Follistatin-344
PreclinicalFollistatin-344 (FST-344)
- Category
- Growth Hormone
- Aliases
- FST-344, FS-344
- Administration
- Subcutaneous injection (preclinical/research use)
Overview
Follistatin-344 is a synthetic version of a naturally occurring human protein that binds and neutralizes myostatin and activin A, two signaling proteins that normally restrain muscle growth. By blocking this natural brake, follistatin-344 is studied for its potential to promote significant increases in muscle mass, distinct from growth-hormone-pathway peptides that stimulate growth rather than remove a limiting signal.
Treatments studied
Treatment categories
Muscle wasting (research interest)
Its myostatin-blocking mechanism is being explored specifically for conditions where preserving or rebuilding muscle mass is a priority.
Sarcopenia
By removing the myostatin brake on muscle growth, it's studied as a potential counter to the age-related muscle loss seen in sarcopenia.