HCG

FDA Approved

Human Chorionic Gonadotropin

Category
Sexual Health
Aliases
hCG, Pregnyl, Novarel
Administration
Subcutaneous injection, Intramuscular injection

How it works

  1. Binds directly to LH receptors on the testes or ovaries, closely mimicking the body's own luteinizing hormone rather than acting upstream at the pituitary.

    Unlike Gonadorelin or Kisspeptin-10, which work further up the hormone chain, hCG acts directly on the testes or ovaries themselves — skipping a step in the signaling process.

  2. In men, this directly stimulates testosterone production and sperm development within the testes; in women, it triggers ovulation by mimicking the natural LH surge.

    That's why it's especially useful for keeping testicular function and size active during testosterone therapy — it directly keeps the testes "working" rather than relying on the brain's signal to reach them.

Result

Directly stimulates the testes or ovaries to produce natural hormone activity — most commonly experienced as maintained testicular size, sperm production, and natural testosterone output in men using it alongside testosterone therapy, or as triggered ovulation in fertility treatment.