Tirzepatide

FDA Approved

Tirzepatide (LY3298176)

Aliases
Mounjaro, Zepbound, LY3298176
Administration
Subcutaneous injection (once weekly)

How it works

  1. Dual GIP receptor agonism

    It mimics a gut hormone (GIP) that helps your body manage blood sugar after eating.

  2. GLP-1 receptor agonism

    It mimics a second gut hormone (GLP-1) that tells your pancreas to release insulin and helps you feel full.

  3. Hypothalamic appetite suppression

    It acts on the brain's hunger control center to reduce how much you want to eat.

  4. Improves insulin sensitivity

    It helps your body's cells respond better to insulin, making it easier to keep blood sugar in a healthy range.

  5. Slows gastric emptying

    It slows how quickly food leaves your stomach, which extends feelings of fullness.

Result

Significant, sustained weight loss and better blood sugar control, driven by reduced appetite and slower digestion. Most people notice they feel full faster and stay full longer, along with steady, visible weight loss and looser-fitting clothes over weeks to months.