Dihexa

Research

Dihexa (PNB-0408)

Aliases
PNB-0408
Administration
Oral (research), Intranasal (research)

How it works

  1. Potentiates the HGF/c-Met receptor pathway

    It amplifies a growth-factor pathway involved in tissue and nerve repair.

  2. Promotes synaptogenesis (new synapse formation) in preclinical models

    In lab animals, it triggered a striking increase in new connections between brain cells.

  3. Crosses the blood-brain barrier via oral or intranasal administration

    Unlike most peptides, it's built to cross into the brain even when swallowed or given as a nasal spray, rather than needing an injection.

Result

In animal studies, a striking increase in new connections between brain cells — a potential path toward treating cognitive decline, though unproven in humans. Since it's never been tested in people, there's no reliable evidence yet for what a person would actually feel or notice.