Semax

Approved (Russia/Ukraine)

Semax

Aliases
ACTH 4-10 analog, Семакс
Administration
Intranasal spray, Subcutaneous injection

Overview

Nootropic peptide that increases BDNF expression and enhances memory, focus, and neuroprotection. Originally developed for stroke rehabilitation in Russia.

Treatments studied

Treatment categories

Cognitive decline

Increases BDNF and supports neurotransmitter systems tied to memory and learning.

Memory impairment

Enhances hippocampal BDNF expression, directly supporting memory formation and retention.

Neurological recovery

Upregulates VEGF, supporting blood vessel and tissue repair in damaged neural tissue.

Stroke rehabilitation

Originally developed in Russia specifically for post-stroke recovery, with neuroprotective and VEGF-driven repair effects.