Humanin
ResearchHumanin (HN)
- Category
- Longevity & Anti-Aging
- Aliases
- Mitochondrial-derived peptide (MDP)
- Administration
- Subcutaneous injection (research)
How it works
- Inhibits apoptosis via interaction with pro-apoptotic proteins (Bax)
It blocks a key signal that tells cells to self-destruct, helping protect stressed or aging cells from dying.
- Binds cell-surface receptors to trigger protective signaling without entering the cell
It attaches to receptors on the outside of cells to trigger a protective response, without needing to enter the cell.
- Improves insulin sensitivity in metabolic studies
In studies, it's improved how well cells respond to insulin.
- Reduces markers of cellular oxidative stress
It helps reduce cell damage caused by oxidative stress.
Result
Protection of stressed or aging cells from premature death, with potential benefits for brain and metabolic health. Because its effects operate at the cellular level, any felt benefit would likely be subtle and long-term rather than something noticeable right away.