IGF-1 LR3

Research

IGF-1 LR3 (Long Arg3-IGF-1)

Category
Growth Hormone
Aliases
Long R3 IGF-1, Long-Arg3-IGF-1
Administration
Subcutaneous injection

How it works

  1. Binds IGF-1 receptors to activate PI3K/Akt and MAPK growth-signaling pathways

    It attaches to IGF-1 receptors and switches on the cellular machinery responsible for tissue growth.

  2. Reduced binding to IGF-binding proteins, extending free/active circulating time

    Normally, binding proteins in your blood quickly deactivate IGF-1 — this version is modified to slip past those binding proteins, so it stays active far longer.

  3. Promotes both hyperplasia and hypertrophy in muscle tissue

    It can prompt muscle tissue to both grow bigger and, unusually, create new muscle cells.

  4. Has insulin-like effects on glucose uptake

    Because it's structurally similar to insulin, it also pulls sugar out of the bloodstream and into cells.

Result

Significant, longer-lasting muscle growth signaling compared to natural IGF-1, due to its extended activity in the body. Used alongside training, this is associated with a fuller, more muscular appearance and faster strength gains, though it also carries a real risk of low blood sugar symptoms like shakiness or dizziness.