Mazdutide

Research Phase

Mazdutide (IBI362)

Aliases
IBI362
Administration
Subcutaneous injection

Overview

Mazdutide is a dual GLP-1 and glucagon receptor agonist developed by Innovent Biologics in partnership with Eli Lilly, sharing a similar dual mechanism to survodutide. It has received regulatory approval in China for weight management and type 2 diabetes, making it one of the first dual GLP-1/glucagon agonists to reach approval anywhere in the world, though it remains investigational and unavailable in the United States.

Treatments studied

Obesity / weight management

Its dual GLP-1/glucagon mechanism is the basis for its regulatory approval in China specifically for weight management.

Type 2 diabetes

Improves blood sugar control through GLP-1 receptor activation, alongside its approved weight-management indication.