N-Acetyl Semax

Research Phase

N-Acetyl Semax Amidate

Aliases
NA Semax, NA-Semax Amidate
Administration
Intranasal

Overview

N-Acetyl Semax Amidate is a chemically modified version of Semax, engineered with an added acetyl group and an amidated end to increase its resistance to breakdown by enzymes in the body. This is intended to extend its duration of action compared to standard Semax, while aiming to preserve the same underlying cognitive and neuroprotective effects tied to BDNF and dopamine signaling.

Treatments studied

Treatment categories

Cognitive decline

Shares Semax's BDNF-elevating mechanism, with structural modifications intended to extend how long each dose remains active.

Stroke rehabilitation

Draws on the same neuroprotective, VEGF-supporting mechanism documented for standard Semax, though independent research specific to this modified analog is more limited.