SLU-PP-332

Research

SLU-PP-332

Aliases
Exercise mimetic ERR agonist
Administration
Oral (research, animal studies)

How it works

  1. Agonist at estrogen-related receptors (ERRα, ERRβ, ERRγ)

    It switches on a set of receptors that exercise normally activates.

  2. Upregulates genes controlling mitochondrial biogenesis

    It tells cells to build more mitochondria, the structures that produce energy.

  3. Shifts muscle fiber composition toward fatigue-resistant, oxidative fibers

    It shifts muscle fibers toward the type used for endurance rather than short bursts of power.

  4. Increases whole-body energy expenditure in animal models

    In mice, it raised how many calories the body burned even without any additional activity.

Result

In mice, endurance and fat-burning capacity similar to what regular exercise produces — without any actual exercise. As a compound untested in humans, there's no current basis for predicting whether a person would feel any exercise-like effect.