Epithalon

Research

Epithalamin / Epitalon

Aliases
Epitalon, Ala-Glu-Asp-Gly
Administration
Subcutaneous injection, Intranasal

Documented benefits

Tier 1 · Peer-reviewed / regulatory

Longevity & Anti-Aging

Epithalon's defining research application — one of the original Khavinson bioregulator peptides studied for lifespan extension.

Anti-aging

Proposed to work at the cellular level by protecting telomeres, the structures that shorten as cells age.

Antioxidant support

Has shown activity upregulating the body's own antioxidant enzyme systems in preclinical studies.

Circadian rhythm regulation

Helps normalize pineal gland melatonin production, supporting the body's natural sleep-wake cycle.

Extended lifespan (animal models)

Extended lifespan in several rodent studies, though this effect has not been confirmed in human trials.

Immune system support

Studied for supporting immune cell function specifically as immune capacity naturally declines with age.

Telomere lengthening

Its core proposed mechanism — activating telomerase to rebuild the protective caps at the ends of chromosomes.