Semax
Approved (Russia/Ukraine)Semax
- Category
- Cognitive & Neuroprotection
- Aliases
- ACTH 4-10 analog, Семакс
- Administration
- Intranasal spray, Subcutaneous injection
Documented benefits
Tier 1 · Peer-reviewed / regulatoryBenefit categories
Cognitive & Neuroprotection
Semax's defining research application — originally developed in Russia specifically for post-stroke neurological recovery.
BDNF elevation
Produces a notably sharp rise in BDNF within the hippocampus, the brain region tied to memory formation.
Cognitive enhancement
Supports mental clarity through combined effects on serotonin, dopamine, and BDNF systems.
Improved memory
Its hippocampal BDNF effect directly supports memory formation and retention.
Improved focus
Users report steadier concentration, consistent with its dopamine and serotonin synthesis effects.
Neuroprotection
Upregulates VEGF, supporting blood vessel and tissue repair in damaged neural tissue.
Stroke recovery support
Its original, defining clinical use in Russia — supporting neurological repair following stroke.