SS-31
Clinical TrialsElamipretide (MTP-131)
- Category
- Longevity & Anti-Aging
- Aliases
- Elamipretide, MTP-131, Bendavia
- Administration
- Subcutaneous injection, IV infusion (clinical)
Documented benefits
Tier 1 · Peer-reviewed / regulatoryBenefit categories
Longevity & Anti-Aging
SS-31's defining research application — directly targeting mitochondrial dysfunction, a hallmark of biological aging.
Anti-aging
Targets the cardiolipin structure in aging mitochondria, addressing a mechanism distinct from most anti-aging peptides.
ATP restoration
Stabilizes cardiolipin, helping mitochondria regain efficient ATP production.
Cardioprotection
Received FDA accelerated approval based specifically on improving mitochondrial energy supply to heart and muscle tissue.
Mitochondrial support
Its core, defining mechanism — binding directly to the inner mitochondrial membrane rather than working through a receptor.
Muscle function
Improved mitochondrial energy supply is linked to better muscle performance, especially under stress.
Reduced oxidative stress
Lowers cell-damaging byproducts specifically generated during mitochondrial energy production.