Ipamorelin

Research

Ipamorelin

Category
Growth Hormone
Aliases
NNC 26-0161
Administration
Subcutaneous injection

Documented benefits

Tier 1 · Peer-reviewed / regulatory

Growth Hormone

Ipamorelin's defining research application — a selective growth hormone secretagogue with minimal off-target hormone effects.

Bone density improvement

Elevated growth hormone and IGF-1 levels support bone remodeling and mineral density over time.

Fat loss

Supports fat loss as a downstream effect of sustained growth hormone elevation rather than a direct metabolic action.

Growth hormone stimulation

Selectively activates the ghrelin receptor (GHS-R1a) to trigger growth hormone release without significantly raising cortisol.

IGF-1 elevation

Growth hormone release drives increased IGF-1 production in the liver, mediating most of its downstream effects.

Muscle growth

Supports lean muscle development through elevated growth hormone and IGF-1 signaling, most effective when paired with training.

Sleep quality improvement

Growth hormone release is naturally tied to deep sleep, and many users report this connection translating to better sleep.