Ipamorelin
ResearchIpamorelin
- Category
- Growth Hormone
- Aliases
- NNC 26-0161
- Administration
- Subcutaneous injection
Documented benefits
Tier 1 · Peer-reviewed / regulatoryBenefit categories
Growth Hormone
Ipamorelin's defining research application — a selective growth hormone secretagogue with minimal off-target hormone effects.
Bone density improvement
Elevated growth hormone and IGF-1 levels support bone remodeling and mineral density over time.
Fat loss
Supports fat loss as a downstream effect of sustained growth hormone elevation rather than a direct metabolic action.
Growth hormone stimulation
Selectively activates the ghrelin receptor (GHS-R1a) to trigger growth hormone release without significantly raising cortisol.
IGF-1 elevation
Growth hormone release drives increased IGF-1 production in the liver, mediating most of its downstream effects.
Muscle growth
Supports lean muscle development through elevated growth hormone and IGF-1 signaling, most effective when paired with training.
Sleep quality improvement
Growth hormone release is naturally tied to deep sleep, and many users report this connection translating to better sleep.