Weight Loss, Appetite & Fat Metabolism

A small-molecule compound (not actually a peptide) that blocks an enzyme tied to fat storage. Popular in longevity circles, but only tested in animals so far.

A lab-made fragment of growth hormone, designed to burn fat without any of growth hormone's other effects. Human trials didn't show it actually works better than placebo.

A long-acting amylin-mimicking peptide best known as half of Novo Nordisk's CagriSema combo. Works alongside GLP-1 drugs to suppress appetite even further.

A long-acting growth hormone booster, often paired with Ipamorelin for steady, round-the-clock growth hormone support.

A potent growth-hormone-releasing peptide, used in Japan as a diagnostic test for growth hormone deficiency. Also mildly stimulates appetite, unlike some newer alternatives.

One of the original growth-hormone-releasing peptides, known for combining strong GH stimulation with a pronounced appetite-boosting effect.

The natural gut hormone that Ozempic and Wegovy are modeled on. Your body already makes it — it just breaks down in minutes, which is why drug versions had to be re-engineered to last longer.

A once-daily pill that raises growth hormone the same way injectable growth hormone-releasing peptides do — but it's chemically a small molecule, not an actual peptide, which is why it can be taken orally.

A heavily modified, long-lasting version of IGF-1 — the hormone that does most of growth hormone's actual muscle-building work — engineered to stay active in the body far longer than the natural version.

A gentle growth hormone booster that signals your pituitary gland to release more growth hormone — without the jittery side effects of older compounds.

A dual GLP-1/glucagon receptor agonist approved in China for weight management, combining appetite suppression with increased energy expenditure.

A peptide made inside your own mitochondria that mimics the metabolic benefits of exercise — improving energy and blood sugar control.

An experimental triple-hormone injection from Eli Lilly showing the biggest weight-loss results of any drug tested so far. Not yet approved — still in late-stage trials.

The FDA-approved GLP-1 behind Ozempic and Wegovy. Reduces appetite, blood sugar, and heart disease risk.

An 'exercise in a pill' compound that made mice run further without training, by switching on the same genetic pathway exercise activates. Not a peptide, and untested in humans.

An investigational dual GLP-1/glucagon receptor agonist in Phase 3 trials, designed to combine appetite suppression with increased calorie burning.

One of the few growth-hormone peptides that's actually FDA approved — but only for a specific fat-redistribution condition in HIV patients. Any other use is off-label.

An FDA-approved weekly injection for diabetes and weight loss. Delivers the strongest results of any approved weight-loss medication to date.