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Growth Hormone Axis & IGF-1 Signaling

Follistatin-344

Growth Hormone

Preclinical

A myostatin-blocking research protein studied for promoting muscle growth by removing a natural brake on muscle development, rather than stimulating growth hormone.

GHRP-2

Growth Hormone

Approved (multiple countries)

A potent growth-hormone-releasing peptide, used in Japan as a diagnostic test for growth hormone deficiency. Also mildly stimulates appetite, unlike some newer alternatives.

GHRP-6

Growth Hormone

Research Phase

One of the original growth-hormone-releasing peptides, known for combining strong GH stimulation with a pronounced appetite-boosting effect.

Hexarelin

Growth Hormone

Research Phase

One of the most potent growth-hormone-releasing peptides studied, with a distinct cardioprotective effect separate from its GH-stimulating activity.

Ibutamoren

Growth Hormone

Research

A once-daily pill that raises growth hormone the same way injectable growth hormone-releasing peptides do — but it's chemically a small molecule, not an actual peptide, which is why it can be taken orally.

IGF-1 LR3

Growth Hormone

Research

A heavily modified, long-lasting version of IGF-1 — the hormone that does most of growth hormone's actual muscle-building work — engineered to stay active in the body far longer than the natural version.

MGF

Growth Hormone

Research

A natural muscle-repair signal your body releases after intense exercise or injury. The synthetic version sold online is chemically unstable and breaks down almost immediately.

PEG-MGF

Growth Hormone

Preclinical

A pegylated, longer-acting version of MGF, engineered to overcome standard MGF's extremely short stability window.

Sermorelin

Growth Hormone

FDA Approved

A growth-hormone-releasing peptide that was actually FDA approved decades ago — the brand was pulled from the market for business reasons, not safety concerns, and it's still available today through compounding pharmacies.

Tesamorelin

Growth Hormone

FDA Approved

One of the few growth-hormone peptides that's actually FDA approved — but only for a specific fat-redistribution condition in HIV patients. Any other use is off-label.