NAD+
ResearchNicotinamide Adenine Dinucleotide
- Category
- Longevity & Anti-Aging
- Aliases
- Coenzyme I, NAD
- Administration
- IV infusion, Subcutaneous injection, Oral (as precursors NMN/NR)
Overview
NAD+ is an essential coenzyme present in every living cell, central to energy metabolism, mitochondrial function, and DNA repair. Levels decline significantly with age, driving substantial research and commercial interest in NAD+ infusions and precursor supplements as longevity interventions, though direct NAD+ administration protocols remain far less standardized than the basic science behind it. Featured in the Trinity Stack.
Treatments studied
Treatment categories
Age-related energy decline (popular use)
Directly replenishes a coenzyme essential for mitochondrial energy production that declines with age.
Addiction recovery support (some clinics, limited evidence)
Some clinics use NAD+ infusions to support energy and mood during recovery, though evidence remains limited.