NAD+

Research

Nicotinamide Adenine Dinucleotide

Aliases
Coenzyme I, NAD
Administration
IV infusion, Subcutaneous injection, Oral (as precursors NMN/NR)

Research and regulatory

Development stage

Extensively studied basic biology; clinical trials of NAD+ precursors (NR, NMN) ongoing, direct NAD+ infusion less rigorously studied in controlled human trials.

Legal and regulatory

Available as a dietary supplement precursor and via IV infusion clinics; not an FDA-approved drug for anti-aging.

Side effects

Flushing, nausea, chest tightness during rapid IV infusion; generally well-tolerated at slower infusion rates