NAD+

Research

Nicotinamide Adenine Dinucleotide

Aliases
Coenzyme I, NAD
Administration
IV infusion, Subcutaneous injection, Oral (as precursors NMN/NR)

Documented side effects

Tier 1 · Peer-reviewed / regulatory

Flushing

A temporary warm, reddened sensation in the skin, typically resolving on its own.

Nausea

A common digestive side effect, often most noticeable when starting or increasing the dose.

Chest tightness (during rapid IV infusion)

A brief, uncomfortable pressure sensation that can occur if an infusion is administered too quickly.

Generally well-tolerated at slower infusion rates

Reducing the speed of administration tends to minimize discomfort.