Pentosan Polysulfate

FDA Approved

Pentosan Polysulfate Sodium

Aliases
PPS, Elmiron
Administration
Oral, Intraarticular injection (research)

Documented side effects

Tier 1 · Peer-reviewed / regulatory

GI effects

General gastrointestinal discomfort, such as nausea or stomach upset.

Rare retinal pigmentary maculopathy (long-term use)

A rare eye condition affecting the retina has been associated with extended use, warranting periodic eye exams.